产品货号:
Z17538
中文名称:
GAD1抗体
英文名称:
Anti-GAD1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GAD1 Antibody |
指标别名 | GAD;GAD 67;GAD1;GAD67;Glutamate decarboxylase 1;SCP |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC |
基因名称 | GAD1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human GAD67(529-543aa PQRREKLHKVAPKIK),different from the related mouse and rat sequences by two amino acids. |
实际分子量 | 67KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Glutamic acid decarboxylase(GAD) catalyses the conversion of L-glutamic acid to the inhibitory neurotransmitter gamma-aminobutyric acid(GABA).Two forms of human GAD,GAD65 and GAD67,are encoded by two separate genes.Human GAD65 cDNA encodes a Mr 65,000 polypeptide,with 585 amino acid residues,whereas human GAD67 encodes a Mr 67,000 polypeptide,with 594 amino acid residues.GAD67 gene consists of 16 exons,spread over more than 45kb of genomic DNA.The GAD67 gene contains an additional exon(exon 0) that together with part of exon 1,specifies the 5' untranslated region of GAD67 mRNA.Human GAD67 shows 65% identity to GAD65 and is located in 2q31.GAD67 may play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. |
Uniprot ID | Q99259 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | glutamate decarboxylase 1(brain,67kDa) |
蛋白名全称 | Glutamate decarboxylase 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry 1:50~400 |
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